Carefully evaluate factors like material compatibility, operating pressure, and temperature requirements to ensure long-term reliability. The decision often involves comparing different fitting types—such as push-to-connect, barbed, or compression fittings—based on the system’s flow rate and specific application demands. Selecting the wrong fitting can lead to leaks, inefficiencies, or premature failure, so understanding thread standards, such as NPT or BSPT, and assessing how fittings interact with tubing materials like polyurethane, nylon, or stainless steel, is key.